12 sourced pigment and dye records, including several with real documented health hazards — stated plainly, with a safety caveat, never as production instructions.

Ultramarine (natural)
Medieval period to 19th century (before synthetic ultramarine)
Extremely expensive — for centuries one of the costliest pigments available, often priced comparably to gold.
Photo: “Ultramarine pigment” by Palladian, Public domain, via Wikimedia Commons.

Indigo
Antiquity to the late 19th century (before synthetic indigo)
A major historical trade commodity; cost varied by region and period but was widely traded internationally.
Photo: “Indigo Dyed Yarn” by Loggie-log, Public domain, via Wikimedia Commons.

Vermilion / Cinnabar
Antiquity to 19th century (largely replaced by cadmium red in the 20th)
Moderately to highly valued depending on period and source purity.
High toxicity
Photo: “Cinnabar from Czech Republic” by Jan Helebrant, CC BY-SA 2.0, via Wikimedia Commons.

Prussian Blue
18th century to present
Significantly cheaper than natural ultramarine, making a strong blue pigment widely affordable for the first time.
Low toxicity
Photo: “Pigment Berliner Blau” by Saalebaer, CC0 1.0, via Wikimedia Commons.