Natural · Antiquity to 19th century (largely replaced by cadmium red in the 20th)

Cinnabar (mercury sulfide) is the natural mineral historically ground to produce vermilion pigment — a real, documented toxicity that any historical vermilion object should be handled with care around.
The grey/tan host rock fills most of this close-up photograph, so an automated whole-frame scan would be dominated by rock rather than the cinnabar itself — the palette above was hand-picked from the visible red mineral."Cinnabar from Czech Republic" by Jan Helebrant, CC BY-SA 2.0, via Wikimedia CommonsHigh toxicity
Contains mercury; historically handled with far less protection than modern safety standards would require.
Mercury-based; historical objects containing this pigment should not be handled without appropriate conservation-level care. Not used in modern consumer paint.